Comparison of Immediate vs Deferred Cytoreductive Nephrectomy in Patients With Synchronous Metastatic Renal Cell Carcinoma Receiving Sunitinib: The SURTIME Randomized Clinical Trial

IMPORTANCE: In clinical practice, patients with primary metastatic renal cell carcinoma (mRCC) have been offered cytoreductive nephrectomy (CN) followed by targeted therapy, but the optimal sequence of surgery and systemic therapy is unknown. OBJECTIVE: To examine whether a period of sunitinib thera...

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Publicat a:JAMA Oncol
Autors principals: Bex, Axel, Mulders, Peter, Jewett, Michael, Wagstaff, John, van Thienen, Johannes V., Blank, Christian U., van Velthoven, Roland, del Pilar Laguna, Maria, Wood, Lori, van Melick, Harm H. E., Aarts, Maureen J., Lattouf, J. B., Powles, Thomas, de Jong, MD, PhD, Igle Jan, Rottey, Sylvie, Tombal, Bertrand, Marreaud, Sandrine, Collette, Sandra, Collette, Laurence, Haanen, John
Format: Artigo
Idioma:Inglês
Publicat: American Medical Association 2018
Matèries:
Original Investigation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6439568/
https://ncbi.nlm.nih.gov/pubmed/30543350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2018.5543
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