Comparison of Immediate vs Deferred Cytoreductive Nephrectomy in Patients With Synchronous Metastatic Renal Cell Carcinoma Receiving Sunitinib: The SURTIME Randomized Clinical Trial

IMPORTANCE: In clinical practice, patients with primary metastatic renal cell carcinoma (mRCC) have been offered cytoreductive nephrectomy (CN) followed by targeted therapy, but the optimal sequence of surgery and systemic therapy is unknown. OBJECTIVE: To examine whether a period of sunitinib thera...

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Detalhes bibliográficos
Publicado no:JAMA Oncol
Main Authors: Bex, Axel, Mulders, Peter, Jewett, Michael, Wagstaff, John, van Thienen, Johannes V., Blank, Christian U., van Velthoven, Roland, del Pilar Laguna, Maria, Wood, Lori, van Melick, Harm H. E., Aarts, Maureen J., Lattouf, J. B., Powles, Thomas, de Jong, MD, PhD, Igle Jan, Rottey, Sylvie, Tombal, Bertrand, Marreaud, Sandrine, Collette, Sandra, Collette, Laurence, Haanen, John
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2018
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6439568/
https://ncbi.nlm.nih.gov/pubmed/30543350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2018.5543
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