Deleterious Mutations in DNA Repair Gene FANCC Exist in BRCA1/2-Negative Chinese Familial Breast and/or Ovarian Cancer Patients

Introduction: FANCC is reported as a novel susceptibility gene for breast cancer, however, its mutation remains unclear in Chinese population. We aimed to identify the germline mutations of FANCC in high-risk breast cancer patients in China. Methods: 255 BRCA1/2-negative Chinese familial breast and/...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Pan, Zhi-Wen, Wang, Xiao-Jia, Chen, Tianhui, Ding, Xiao-Wen, Jiang, Xiyi, Gao, Yun, Mo, Wen-Ju, Huang, Yuan, Lou, Cai-Jin, Cao, Wen-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6439399/
https://ncbi.nlm.nih.gov/pubmed/30967997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00169
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