Effects of HIV-1 Tat on oligodendrocyte viability are mediated by CaMKIIβ-GSK3β interaction

Myelin disruptions are frequently reported in human immunodeficiency virus (HIV)-infected individuals and can occur in the CNS very early in the disease process. Immature oligodendrocytes (OLs) are quite sensitive to toxic increases in [Ca2+]i caused by exposure to HIV-1 Tat (transactivator of trans...

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發表在:J Neurochem
Main Authors: Zou, Shiping, Balinang, Joyce M., Paris, Jason J., Hauser, Kurt F., Fuss, Babette, Knapp, Pamela E.
格式: Artigo
語言:Inglês
出版: 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6438763/
https://ncbi.nlm.nih.gov/pubmed/30674062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.14668
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