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Effects of HIV-1 Tat on oligodendrocyte viability are mediated by CaMKIIβ-GSK3β interaction
Myelin disruptions are frequently reported in human immunodeficiency virus (HIV)-infected individuals and can occur in the CNS very early in the disease process. Immature oligodendrocytes (OLs) are quite sensitive to toxic increases in [Ca2+]i caused by exposure to HIV-1 Tat (transactivator of trans...
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| Publicado no: | J Neurochem |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6438763/ https://ncbi.nlm.nih.gov/pubmed/30674062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.14668 |
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