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Neutrophil extracellular trap fragments stimulate innate immune responses that prevent lung transplant tolerance

Neutrophil extracellular traps (NETs) have been shown to worsen acute pulmonary injury including after lung transplantation. The breakdown of NETs by DNAse-1 can help restore lung function, but whether there is an impact on allograft tolerance remains less clear. Using intravital 2-photon microscopy...

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Detalhes bibliográficos
Publicado no:Am J Transplant
Main Authors: Scozzi, Davide, Wang, Xingan, Liao, Fuyi, Liu, Zhiyi, Zhu, Jihong, Pugh, Katy, Ibrahim, Mohsen, Hsiao, Hsi-Min, Miller, Mark J., Yizhan, Guo, Mohanakumar, Thalachallour, Krupnick, Alexander S., Kreisel, Daniel, Gelman, Andrew E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6438629/
https://ncbi.nlm.nih.gov/pubmed/30378766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.15163
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