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Evidence that alternative transcriptional initiation is largely nonadaptive

Alternative transcriptional initiation (ATI) refers to the frequent observation that one gene has multiple transcription start sites (TSSs). Although this phenomenon is thought to be adaptive, the specific advantage is rarely known. Here, we propose that each gene has one optimal TSS and that ATI ar...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Xu, Chuan, Park, Joong-Ki, Zhang, Jianzhi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6438578/
https://ncbi.nlm.nih.gov/pubmed/30883542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000197
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