Sfrp5 increases glucose-stimulated insulin secretion in the rat pancreatic beta cell line INS-1E

Previous studies reported that secreted frizzled-related protein-5 (Sfrp5) decreases beta cell proliferation and increases fasting insulin levels, but studies on direct effects of Sfrp5 on insulin secretion and its underlying mechanisms are missing. This study examined effects of Sfrp5 on (i) beta c...

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Sparad:
Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Carstensen-Kirberg, Maren, Röhrig, Karin, Niersmann, Corinna, Ouwens, D. Margriet, Belgardt, Bengt F., Roden, Michael, Herder, Christian
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2019
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6438539/
https://ncbi.nlm.nih.gov/pubmed/30921355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0213650
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