Sfrp5 increases glucose-stimulated insulin secretion in the rat pancreatic beta cell line INS-1E

Previous studies reported that secreted frizzled-related protein-5 (Sfrp5) decreases beta cell proliferation and increases fasting insulin levels, but studies on direct effects of Sfrp5 on insulin secretion and its underlying mechanisms are missing. This study examined effects of Sfrp5 on (i) beta c...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Carstensen-Kirberg, Maren, Röhrig, Karin, Niersmann, Corinna, Ouwens, D. Margriet, Belgardt, Bengt F., Roden, Michael, Herder, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6438539/
https://ncbi.nlm.nih.gov/pubmed/30921355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0213650
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