Sfrp5 increases glucose-stimulated insulin secretion in the rat pancreatic beta cell line INS-1E

Previous studies reported that secreted frizzled-related protein-5 (Sfrp5) decreases beta cell proliferation and increases fasting insulin levels, but studies on direct effects of Sfrp5 on insulin secretion and its underlying mechanisms are missing. This study examined effects of Sfrp5 on (i) beta c...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Carstensen-Kirberg, Maren, Röhrig, Karin, Niersmann, Corinna, Ouwens, D. Margriet, Belgardt, Bengt F., Roden, Michael, Herder, Christian
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6438539/
https://ncbi.nlm.nih.gov/pubmed/30921355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0213650
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