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The nature and intensity of mechanical stimulation drive different dynamics of MRTF-A nuclear redistribution after actin remodeling in myoblasts

Serum response factor and its cofactor myocardin-related transcription factor (MRTF) are key elements of muscle-mass adaptation to workload. The transcription of target genes is activated when MRTF is present in the nucleus. The localization of MRTF is controlled by its binding to G-actin. Thus, the...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Montel, Lorraine, Sotiropoulos, Athanassia, Hénon, Sylvie
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6438519/
https://ncbi.nlm.nih.gov/pubmed/30921405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0214385
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