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Mutant Actins Demonstrate a Role for Unpolymerized Actin in Control of Transcription by Serum Response Factor
Signal-induced activation of the transcription factor serum response factor (SRF) requires alterations in actin dynamics. SRF activity can be inhibited by ectopic expression of β-actin, either because actin itself participates in SRF regulation or as a consequence of cytoskeletal perturbations. To d...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC138624/ https://ncbi.nlm.nih.gov/pubmed/12475943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.02-05-0068 |
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