Emodin alleviates myocardial ischemia/reperfusion injury by inhibiting gasdermin D-mediated pyroptosis in cardiomyocytes

BACKGROUND: Emodin has recently been reported to have a powerful antiinflammatory effect, protecting the myocardium against ischemia/reperfusion (I/R) injury. Pyroptosis is a proinflammatory programmed cell death that is related to many diseases. The present study investigated the effect of emodin o...

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Bibliografiske detaljer
Udgivet i:Drug Des Devel Ther
Main Authors: Ye, Bozhi, Chen, Xudong, Dai, Shanshan, Han, Jibo, Liang, Xiaohe, Lin, Shuang, Cai, Xueli, Huang, Zhouqing, Huang, Weijian
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2019
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6438141/
https://ncbi.nlm.nih.gov/pubmed/30988600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S195412
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