Interleukin-10 inhibits interleukin-1β production and inflammasome activation of microglia in epileptic seizures

BACKGROUND: Microglia are important for secreting chemical mediators of inflammatory responses in the central nervous system. Interleukin (IL)-10 and IL-1β secreted by glial cells support neuronal functions, but the related mechanisms remain vague. Our goal was to demonstrate the efficacy of IL-10 i...

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Dades bibliogràfiques
Publicat a:J Neuroinflammation
Autors principals: Sun, Yi, Ma, Jiangjun, Li, Dongfang, Li, Pinggan, Zhou, Xiaolin, Li, Yu, He, Zhanwen, Qin, Lijun, Liang, Liyang, Luo, Xiangyang
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6437919/
https://ncbi.nlm.nih.gov/pubmed/30922332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1452-1
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