miR-132-3p is a positive regulator of alpha-cell mass and is downregulated in obese hyperglycemic mice

OBJECTIVE: Diabetes is a complex disease implicating several organs and cell types. Within the islets, dysregulation occurs in both alpha- and beta-cells, leading to defects of insulin secretion and increased glucagon secretion. Dysregulation of alpha-cells is associated with transcriptome changes....

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Dusaulcy, Rodolphe, Handgraaf, Sandra, Visentin, Florian, Vesin, Christian, Philippe, Jacques, Gosmain, Yvan
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6437597/
https://ncbi.nlm.nih.gov/pubmed/30711402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2019.01.004
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