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miR-132-3p is a positive regulator of alpha-cell mass and is downregulated in obese hyperglycemic mice
OBJECTIVE: Diabetes is a complex disease implicating several organs and cell types. Within the islets, dysregulation occurs in both alpha- and beta-cells, leading to defects of insulin secretion and increased glucagon secretion. Dysregulation of alpha-cells is associated with transcriptome changes....
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| 出版年: | Mol Metab |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Elsevier
2019
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6437597/ https://ncbi.nlm.nih.gov/pubmed/30711402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2019.01.004 |
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