Intratibial Injection Causes Direct Pulmonary Seeding of Osteosarcoma Cells and Is Not a Spontaneous Model of Metastasis: A Mouse Osteosarcoma Model

BACKGROUND: Although metastasis is the major cause of mortality in patients with osteosarcoma, little is known about how micrometastases progress to gross metastatic disease. Clinically relevant animal models are necessary to facilitate development of new therapies to target indolent pulmonary metas...

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Detaylı Bibliyografya
Yayımlandı:Clin Orthop Relat Res
Asıl Yazarlar: Maloney, Caroline, Edelman, Morris C., Kallis, Michelle P., Soffer, Samuel Z., Symons, Marc, Steinberg, Bettie M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Wolters Kluwer 2018
Konular:
Basic Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6437576/
https://ncbi.nlm.nih.gov/pubmed/29601385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11999.0000000000000291
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