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Iron/Heme Metabolism-Targeted Gallium(III) Nanoparticles Are Active against Extracellular and Intracellular Pseudomonas aeruginosa and Acinetobacter baumannii

Iron/heme acquisition systems are critical for microorganisms to acquire iron from the human host, where iron sources are limited due to the nutritional immune system and insolubility of the ferric form of iron. Prior work has shown that a variety of gallium compounds can interfere with bacterial ir...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Choi, Seoung-ryoung, Britigan, Bradley E., Narayanasamy, Prabagaran
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6437536/
https://ncbi.nlm.nih.gov/pubmed/30782994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02643-18
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