The Anthelmintic Drug Niclosamide Synergizes with Colistin and Reverses Colistin Resistance in Gram-Negative Bacilli

There is an urgent need for new therapies to overcome antimicrobial resistance especially in Gram-negative bacilli (GNB). Repurposing old U.S. Food and Drug Administration-approved drugs as complementary agents to existing antibiotics in a synergistic combination presents an attractive strategy. Her...

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Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Domalaon, Ronald, De Silva, P. Malaka, Kumar, Ayush, Zhanel, George G., Schweizer, Frank
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2019
Schlagworte:
Susceptibility
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6437516/
https://ncbi.nlm.nih.gov/pubmed/30917988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02574-18
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