Characterization of Hypermutator Pseudomonas aeruginosa Isolates from Patients with Cystic Fibrosis in Australia

Hypermutable Pseudomonas aeruginosa isolates (hypermutators) have been identified in patients with cystic fibrosis (CF) and are associated with reduced lung function. Hypermutators display a greatly increased mutation rate and an enhanced ability to become resistant to antibiotics during treatment....

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Pubblicato in:Antimicrob Agents Chemother
Autori principali: Rees, Vanessa E., Deveson Lucas, Deanna S., López-Causapé, Carla, Huang, Yuling, Kotsimbos, Tom, Bulitta, Jürgen B., Rees, Murray C., Barugahare, Adele, Peleg, Anton Y., Nation, Roger L., Oliver, Antonio, Boyce, John D., Landersdorfer, Cornelia B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2019
Soggetti:
Mechanisms of Resistance
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6437500/
https://ncbi.nlm.nih.gov/pubmed/30745381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02538-18
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