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Iron Chelator Deferasirox Reduces Candida albicans Invasion of Oral Epithelial Cells and Infection Levels in Murine Oropharyngeal Candidiasis

Candida albicans, the causative agent of mucosal infections, including oropharyngeal candidiasis (OPC), as well as bloodstream infections, is becoming increasingly resistant to existing treatment options. In the absence of novel drug candidates, drug repurposing aimed at using existing drugs to trea...

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Foilsithe in:Antimicrob Agents Chemother
Main Authors: Puri, Sumant, Kumar, Rohitashw, Rojas, Isolde G., Salvatori, Ornella, Edgerton, Mira
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6437492/
https://ncbi.nlm.nih.gov/pubmed/30718249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02152-18
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