Secreted Aspartic Protease Cleavage of Candida albicans Msb2 Activates Cek1 MAPK Signaling Affecting Biofilm Formation and Oropharyngeal Candidiasis

Perception of external stimuli and generation of an appropriate response are crucial for host colonization by pathogens. In pathogenic fungi, mitogen activated protein kinase (MAPK) pathways regulate dimorphism, biofilm/mat formation, and virulence. Signaling mucins, characterized by a heavily glyco...

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Detalhes bibliográficos
Main Authors: Puri, Sumant, Kumar, Rohitashw, Chadha, Sonia, Tati, Swetha, Conti, Heather R., Hube, Bernhard, Cullen, Paul J., Edgerton, Mira
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491010/
https://ncbi.nlm.nih.gov/pubmed/23139737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046020
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