Secreted Aspartic Protease Cleavage of Candida albicans Msb2 Activates Cek1 MAPK Signaling Affecting Biofilm Formation and Oropharyngeal Candidiasis

Perception of external stimuli and generation of an appropriate response are crucial for host colonization by pathogens. In pathogenic fungi, mitogen activated protein kinase (MAPK) pathways regulate dimorphism, biofilm/mat formation, and virulence. Signaling mucins, characterized by a heavily glyco...

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Bibliografske podrobnosti
Main Authors: Puri, Sumant, Kumar, Rohitashw, Chadha, Sonia, Tati, Swetha, Conti, Heather R., Hube, Bernhard, Cullen, Paul J., Edgerton, Mira
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491010/
https://ncbi.nlm.nih.gov/pubmed/23139737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046020
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