Secreted Aspartic Protease Cleavage of Candida albicans Msb2 Activates Cek1 MAPK Signaling Affecting Biofilm Formation and Oropharyngeal Candidiasis

Perception of external stimuli and generation of an appropriate response are crucial for host colonization by pathogens. In pathogenic fungi, mitogen activated protein kinase (MAPK) pathways regulate dimorphism, biofilm/mat formation, and virulence. Signaling mucins, characterized by a heavily glyco...

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Bibliographische Detailangaben
Hauptverfasser: Puri, Sumant, Kumar, Rohitashw, Chadha, Sonia, Tati, Swetha, Conti, Heather R., Hube, Bernhard, Cullen, Paul J., Edgerton, Mira
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491010/
https://ncbi.nlm.nih.gov/pubmed/23139737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046020
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