Unilateral ureteral obstruction causes gut microbial dysbiosis and metabolome disorders contributing to tubulointerstitial fibrosis

Chronic kidney disease (CKD) increases the risk and prevalence of cardiovascular disease (CVD) morbidity and mortality. Recent studies have revealed marked changes in the composition of the microbiome and the metabolome and their potential influence in renal disease and CVD via the accumulation of m...

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Veröffentlicht in:Exp Mol Med
Hauptverfasser: Chen, Lin, Chen, Dan-Qian, Liu, Jing-Ru, Zhang, Jun, Vaziri, Nosratola D., Zhuang, Shougang, Chen, Hua, Feng, Ya-Long, Guo, Yan, Zhao, Ying-Yong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6437207/
https://ncbi.nlm.nih.gov/pubmed/30918245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-019-0234-2
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