Notch signaling in the collecting duct regulates renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction in mice

BACKGROUND/AIMS: Mind bomb-1 (Mib1) encodes an E3 ubiquitin ligase, which is required for the initiation of Notch signaling. Recently, it was demonstrated that the renal collecting duct plays an important role in renal fibrosis. Here, we investigated the role of Notch signaling in renal fibrosis usi...

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Veröffentlicht in:Korean J Intern Med
Hauptverfasser: Choi, Arum, Nam, Sun Ah, Kim, Wan-Young, Park, Sang Hee, Kim, Hyang, Yang, Chul Woo, Kim, Jin, Kim, Yong Kyun
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Korean Association of Internal Medicine 2018
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030409/
https://ncbi.nlm.nih.gov/pubmed/28602064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3904/kjim.2016.230
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