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Entry of Polarized Effector Cells into Quiescence Forces HIV Latency

The latent HIV reservoir is generated following HIV infection of activated effector CD4 T cells, which then transition to a memory phenotype. Here, we describe an ex vivo method, called QUECEL (quiescent effector cell latency), that mimics this process efficiently and allows production of large numb...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Dobrowolski, Curtis, Valadkhan, Saba, Graham, Amy C., Shukla, Meenakshi, Ciuffi, Angela, Telenti, Amalio, Karn, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6437053/
https://ncbi.nlm.nih.gov/pubmed/30914509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00337-19
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