Antagonism of dsRNA-Induced Innate Immune Pathways by NS4a and NS4b Accessory Proteins during MERS Coronavirus Infection

Middle East respiratory syndrome coronavirus (MERS-CoV) was first identified in 2012 as a novel etiological agent of severe respiratory disease in humans. As during infection by other viruses, host sensing of viral double-stranded RNA (dsRNA) induces several antiviral pathways. These include interfe...

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Publicat a:mBio
Autors principals: Comar, Courtney E., Goldstein, Stephen A., Li, Yize, Yount, Boyd, Baric, Ralph S., Weiss, Susan R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6437052/
https://ncbi.nlm.nih.gov/pubmed/30914508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00319-19
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