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Learning protein constitutive motifs from sequence data

Statistical analysis of evolutionary-related protein sequences provides information about their structure, function, and history. We show that Restricted Boltzmann Machines (RBM), designed to learn complex high-dimensional data and their statistical features, can efficiently model protein families f...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Tubiana, Jérôme, Cocco, Simona, Monasson, Rémi
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6436896/
https://ncbi.nlm.nih.gov/pubmed/30857591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.39397
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