Postnatal deletion of Alk5 gene in meniscal cartilage accelerates age-dependent meniscal degeneration in mice

Activation of transforming growth factor-β (TGF-β) signaling has been used to enhance healing of meniscal degeneration in several models. However, the exact role and molecular mechanism of TGF-β signaling in meniscus maintenance and degeneration are still not understood due to the absence of in vivo...

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Udgivet i:J Cell Physiol
Main Authors: Wang, Quan, Tan, Qiaoyan, Xu, Wei, Kuang, Liang, Zhang, Bin, Wang, Zuqiang, Ni, Zhenhong, Su, Nan, Jin, Min, Li, Can, Jiang, Wanling, Huang, Junlan, Li, Fangfang, Zhu, Ying, Chen, Hangang, Du, Xiaolan, Chen, Di, Deng, Chuxia, Qi, Huabing, Xie, Yangli, Chen, Lin
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6436632/
https://ncbi.nlm.nih.gov/pubmed/30078186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.26802
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