PET imaging of the influence of physiological and pathological α‐synuclein on dopaminergic and serotonergic neurotransmission in mouse models

AIMS: Alpha‐synuclein (α‐syn) aggregation is a neuropathological hallmark of neurodegenerative synucleinopathies. This in vivo study explored glucose metabolism and dopaminergic and serotoninergic neurotransmission in KO α‐syn, wild‐type mice and an accelerated murine model of synucleinopathy (M83)....

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Bibliografiske detaljer
Udgivet i:CNS Neurosci Ther
Main Authors: Levigoureux, Elise, Bouillot, Caroline, Baron, Thierry, Zimmer, Luc, Lancelot, Sophie
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6436587/
https://ncbi.nlm.nih.gov/pubmed/29781098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12978
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