Alpha-synuclein spreading in M83 mice brain revealed by detection of pathological α-synuclein by enhanced ELISA

BACKGROUND: The accumulation of misfolded proteins appears as a fundamental pathogenic process in human neurodegenerative diseases. In the case of synucleinopathies such as Parkinson’s disease (PD) or dementia with Lewy bodies (DLB), the intraneuronal deposition of aggregated alpha-synuclein (αS) is...

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Detalhes bibliográficos
Main Authors: Bétemps, Dominique, Verchère, Jérémy, Brot, Sébastien, Morignat, Eric, Bousset, Luc, Gaillard, Damien, Lakhdar, Latifa, Melki, Ronald, Baron, Thierry
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007641/
https://ncbi.nlm.nih.gov/pubmed/24624994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2051-5960-2-29
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