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Encircling the regions of the pharmacogenomic landscape that determine drug response

BACKGROUND: The integration of large-scale drug sensitivity screens and genome-wide experiments is changing the field of pharmacogenomics, revealing molecular determinants of drug response without the need for previous knowledge about drug action. In particular, transcriptional signatures of drug se...

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Pubblicato in:Genome Med
Autori principali: Fernández-Torras, Adrià, Duran-Frigola, Miquel, Aloy, Patrick
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6436215/
https://ncbi.nlm.nih.gov/pubmed/30914058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-019-0626-x
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