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Recycling side-effects into clinical markers for drug repositioning

Side-effects are the unintended consequence of therapeutic treatments, but they can also be seen as valuable read-outs of drug effects in humans; these effects are difficult to infer or predict from pre-clinical models. Indeed, some studies suggest that drugs with similar side-effect profiles may al...

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Bibliografske podrobnosti
Main Authors: Duran-Frigola, Miquel, Aloy, Patrick
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334551/
https://ncbi.nlm.nih.gov/pubmed/22283977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm302
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