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The effect of the antisickling compound GBT1118 on the permeability of red blood cells from patients with sickle cell anemia

Sickle cell anemia (SCA) is one of the commonest severe inherited disorders. Nevertheless, effective treatments remain inadequate and novel ones are avidly sought. A promising advance has been the design of novel compounds which react with hemoglobin S (HbS) to increase oxygen (O(2)) affinity and re...

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Detalles Bibliográficos
Publicado en:Physiol Rep
Main Authors: Al Balushi, Halima, Dufu, Kobina, Rees, David C., Brewin, John N., Hannemann, Anke, Oksenberg, Donna, Lu, David C.‐Y., Gibson, John S.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6436144/
https://ncbi.nlm.nih.gov/pubmed/30916477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14027
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