Establishment of Immunoglobulin Heavy (IGH) Chain Clonality Testing by Next-Generation Sequencing for Routine Characterization of B-Cell and Plasma Cell Neoplasms

Immunoglobulin heavy chain (IGH) clonality testing by next-generation sequencing (NGS) offers unique advantages over current low-throughput methods in the assessment of B-cell lineage neoplasms. Clinical use remains limited because assays are not standardized and validation/implementation guidelines...

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Detalhes bibliográficos
Publicado no:J Mol Diagn
Main Authors: Arcila, Maria E., Yu, Wayne, Syed, Mustafa, Kim, Hannah, Maciag, Lidia, Yao, JinJuan, Ho, Caleb, Petrova, Kseniya, Moung, Christine, Salazar, Paulo, Rijo, Ivelise, Baldi, Tessara, Zehir, Ahmet, Landgren, Ola, Park, Jae, Roshal, Mikhail, Dogan, Ahmet, Nafa, Khedoudja
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6436112/
https://ncbi.nlm.nih.gov/pubmed/30590126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmoldx.2018.10.008
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