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Human-specific dual regulations of FXR-activation for reduction of fatty liver using in vitro cell culture model

Nuclear receptor farnesoid X receptor activation inhibits fatty acid synthesis through the liver X receptor-α-sterol regulatory element binding protein-1c pathway universally in animals, but also has human-specific crosstalk with the peroxisome proliferator-activated receptor-α. The effects of farne...

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Библиографические подробности
Опубликовано в: :J Clin Biochem Nutr
Главные авторы: Miyazaki, Teruo, Honda, Akira, Ikegami, Tadashi, Iida, Takashi, Matsuzaki, Yasushi
Формат: Artigo
Язык:Inglês
Опубликовано: the Society for Free Radical Research Japan 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6436045/
https://ncbi.nlm.nih.gov/pubmed/30936623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3164/jcbn.18-80
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