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Effect of chronic opioid therapy on pain and survival in a humanized mouse model of sickle cell disease
Chronic morphine treatment leads to decreased survival in control mice, but not in sickle mice. Chronic morphine treatment leads to hyperalgesia in sickle mice, but does not lead to analgesic tolerance.
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| Publicat a: | Blood Adv |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society of Hematology
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6436015/ https://ncbi.nlm.nih.gov/pubmed/30885998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018024299 |
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