NADPH oxidase 2 inhibitors CPP11G and CPP11H attenuate endothelial cell inflammation & vessel dysfunction and restore mouse hind-limb flow

First described as essential to the phagocytic activity of leukocytes, Nox2-derived ROS have emerged as mediators of a range of cellular and tissue responses across species from salubrious to deleterious consequences. Knowledge of their role in inflammation is limited, however. We postulated that TN...

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Vydáno v:Redox Biol
Hlavní autoři: Li, Y., Cifuentes-Pagano, E., DeVallance, E.R., de Jesus, D.S., Sahoo, S., Meijles, D.N., Koes, D., Camacho, C.J., Ross, M., St Croix, C., Pagano, P.J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2019
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435978/
https://ncbi.nlm.nih.gov/pubmed/30897521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101143
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