Lactate Mediates the Effects of Exercise on Learning and Memory through SIRT1-Dependent Activation of Hippocampal Brain-Derived Neurotrophic Factor (BDNF)

Exercise promotes learning and memory formation. These effects depend on increases in hippocampal BDNF, a growth factor associated with cognitive improvement and the alleviation of depression symptoms. Identifying molecules that are produced during exercise and that mediate hippocampal Bdnf expressi...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: El Hayek, Lauretta, Khalifeh, Mohamad, Zibara, Victor, Abi Assaad, Rawad, Emmanuel, Nancy, Karnib, Nabil, El-Ghandour, Rim, Nasrallah, Patrick, Bilen, Maria, Ibrahim, Pascale, Younes, Joe, Abou Haidar, Edwina, Barmo, Nour, Jabre, Vanessa, Stephan, Joseph S., Sleiman, Sama F.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2019
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435829/
https://ncbi.nlm.nih.gov/pubmed/30692222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1661-18.2019
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