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Antrodia cinnamomea induces anti-tumor activity by inhibiting the STAT3 signaling pathway in lung cancer cells

We examined the effects of an Antrodia cinnamomea ethanol extract (ACEE) on lung cancer cells in vitro and tumor growth in vivo. ACEE produced dose-dependent cytotoxic effects and induced apoptosis in Lewis lung carcinoma (LLC) cells. ACEE treatment increased expression of p53 and Bax, as well as cl...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Huang, Tsung-Teng, Lan, Ying-Wei, Chen, Chuan-Mu, Ko, Yun-Fei, Ojcius, David M., Martel, Jan, Young, John D., Chong, Kowit-Yu
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435735/
https://ncbi.nlm.nih.gov/pubmed/30914735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41653-9
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