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Improved survival prognostication of node-positive malignant melanoma patients utilizing shotgun proteomics guided by histopathological characterization and genomic data

Metastatic melanoma is one of the most common deadly cancers, and robust biomarkers are still needed, e.g. to predict survival and treatment efficiency. Here, protein expression analysis of one hundred eleven melanoma lymph node metastases using high resolution mass spectrometry is coupled with in-d...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Betancourt, Lazaro Hiram, Pawłowski, Krzysztof, Eriksson, Jonatan, Szasz, A. Marcell, Mitra, Shamik, Pla, Indira, Welinder, Charlotte, Ekedahl, Henrik, Broberg, Per, Appelqvist, Roger, Yakovleva, Maria, Sugihara, Yutaka, Miharada, Kenichi, Ingvar, Christian, Lundgren, Lotta, Baldetorp, Bo, Olsson, Håkan, Rezeli, Melinda, Wieslander, Elisabet, Horvatovich, Peter, Malm, Johan, Jönsson, Göran, Marko-Varga, György
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435712/
https://ncbi.nlm.nih.gov/pubmed/30914758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41625-z
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