Improved survival prognostication of node-positive malignant melanoma patients utilizing shotgun proteomics guided by histopathological characterization and genomic data

Metastatic melanoma is one of the most common deadly cancers, and robust biomarkers are still needed, e.g. to predict survival and treatment efficiency. Here, protein expression analysis of one hundred eleven melanoma lymph node metastases using high resolution mass spectrometry is coupled with in-d...

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Publicat a:Sci Rep
Autors principals: Betancourt, Lazaro Hiram, Pawłowski, Krzysztof, Eriksson, Jonatan, Szasz, A. Marcell, Mitra, Shamik, Pla, Indira, Welinder, Charlotte, Ekedahl, Henrik, Broberg, Per, Appelqvist, Roger, Yakovleva, Maria, Sugihara, Yutaka, Miharada, Kenichi, Ingvar, Christian, Lundgren, Lotta, Baldetorp, Bo, Olsson, Håkan, Rezeli, Melinda, Wieslander, Elisabet, Horvatovich, Peter, Malm, Johan, Jönsson, Göran, Marko-Varga, György
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435712/
https://ncbi.nlm.nih.gov/pubmed/30914758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41625-z
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