Improved survival prognostication of node-positive malignant melanoma patients utilizing shotgun proteomics guided by histopathological characterization and genomic data

Metastatic melanoma is one of the most common deadly cancers, and robust biomarkers are still needed, e.g. to predict survival and treatment efficiency. Here, protein expression analysis of one hundred eleven melanoma lymph node metastases using high resolution mass spectrometry is coupled with in-d...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Betancourt, Lazaro Hiram, Pawłowski, Krzysztof, Eriksson, Jonatan, Szasz, A. Marcell, Mitra, Shamik, Pla, Indira, Welinder, Charlotte, Ekedahl, Henrik, Broberg, Per, Appelqvist, Roger, Yakovleva, Maria, Sugihara, Yutaka, Miharada, Kenichi, Ingvar, Christian, Lundgren, Lotta, Baldetorp, Bo, Olsson, Håkan, Rezeli, Melinda, Wieslander, Elisabet, Horvatovich, Peter, Malm, Johan, Jönsson, Göran, Marko-Varga, György
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435712/
https://ncbi.nlm.nih.gov/pubmed/30914758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41625-z
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