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The M(1) muscarinic acetylcholine receptor subtype is important for retinal neuron survival in aging mice

Muscarinic acetylcholine receptors have been implicated as potential neuroprotective targets for glaucoma. We tested the hypothesis that the lack of a single muscarinic receptor subtype leads to age-dependent neuron reduction in the retinal ganglion cell layer. Mice with targeted disruption of singl...

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Publicado en:Sci Rep
Autores principales: Laspas, Panagiotis, Zhutdieva, Mayagozel B., Brochhausen, Christoph, Musayeva, Aytan, Zadeh, Jenia Kouchek, Pfeiffer, Norbert, Xia, Ning, Li, Huige, Wess, Juergen, Gericke, Adrian
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435680/
https://ncbi.nlm.nih.gov/pubmed/30914695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41425-5
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