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The M(1) muscarinic acetylcholine receptor subtype is important for retinal neuron survival in aging mice

Muscarinic acetylcholine receptors have been implicated as potential neuroprotective targets for glaucoma. We tested the hypothesis that the lack of a single muscarinic receptor subtype leads to age-dependent neuron reduction in the retinal ganglion cell layer. Mice with targeted disruption of singl...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Laspas, Panagiotis, Zhutdieva, Mayagozel B., Brochhausen, Christoph, Musayeva, Aytan, Zadeh, Jenia Kouchek, Pfeiffer, Norbert, Xia, Ning, Li, Huige, Wess, Juergen, Gericke, Adrian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435680/
https://ncbi.nlm.nih.gov/pubmed/30914695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41425-5
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