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Utilization of NGS technologies to investigate transcriptomic and epigenomic mechanisms in trastuzumab resistance

NGS (Next Generation Sequencing) technologies allows us to determine key gene expression signatures that correlate with resistance (and responsiveness) to anti-cancer therapeutics. We have undertaken a transcriptomic and chromatin immunoprecipitation followed by sequencing (ChIP-seq) approach to des...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Nava, Miguel, Dutta, Pranabananda, Farias-Eisner, Robin, Vadgama, Jaydutt V., Wu, Yanyuan
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435657/
https://ncbi.nlm.nih.gov/pubmed/30914750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41672-6
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