Utilization of NGS technologies to investigate transcriptomic and epigenomic mechanisms in trastuzumab resistance

NGS (Next Generation Sequencing) technologies allows us to determine key gene expression signatures that correlate with resistance (and responsiveness) to anti-cancer therapeutics. We have undertaken a transcriptomic and chromatin immunoprecipitation followed by sequencing (ChIP-seq) approach to des...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Nava, Miguel, Dutta, Pranabananda, Farias-Eisner, Robin, Vadgama, Jaydutt V., Wu, Yanyuan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435657/
https://ncbi.nlm.nih.gov/pubmed/30914750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41672-6
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