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High glucose level and angiotensin II type 1 receptor stimulation synergistically amplify oxidative stress in renal mesangial cells

Oxidative stress in renal mesangial cell causes diabetic glomerular changes. High glucose levels and angiotensin II (Ang II) are known to stimulate superoxide production in renal mesangial cells. However, it has been unclear whether Ang II stimulation and pre-conditioning with high glucose affects t...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Akaishi, Tetsuya, Abe, Michiaki, Okuda, Hiroshi, Ishizawa, Kota, Abe, Takaaki, Ishii, Tadashi, Ito, Sadayoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435641/
https://ncbi.nlm.nih.gov/pubmed/30914692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41536-z
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