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High glucose level and angiotensin II type 1 receptor stimulation synergistically amplify oxidative stress in renal mesangial cells

Oxidative stress in renal mesangial cell causes diabetic glomerular changes. High glucose levels and angiotensin II (Ang II) are known to stimulate superoxide production in renal mesangial cells. However, it has been unclear whether Ang II stimulation and pre-conditioning with high glucose affects t...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Akaishi, Tetsuya, Abe, Michiaki, Okuda, Hiroshi, Ishizawa, Kota, Abe, Takaaki, Ishii, Tadashi, Ito, Sadayoshi
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435641/
https://ncbi.nlm.nih.gov/pubmed/30914692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41536-z
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