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DNA phosphorothioate modification—a new multi-functional epigenetic system in bacteria
Synthetic phosphorothioate (PT) internucleotide linkages, in which a nonbridging oxygen is replaced by a sulphur atom, share similar physical and chemical properties with phosphodiesters but confer enhanced nuclease tolerance on DNA/RNA, making PTs a valuable biochemical and pharmacological tool. In...
Gorde:
| Argitaratua izan da: | FEMS Microbiol Rev |
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| Egile Nagusiak: | , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Oxford University Press
2018
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6435447/ https://ncbi.nlm.nih.gov/pubmed/30289455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/femsre/fuy036 |
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