Vitamin D stimulates cardiomyocyte proliferation and controls organ size and regeneration in zebrafish

Attaining proper organ size during development and regeneration hinges on activity of mitogenic factors. Here, we performed a large-scale chemical screen in embryonic zebrafish to identify cardiomyocyte mitogens. Although commonly considered antiproliferative, vitamin D analogues like alfacalcidol h...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Han, Yanchao, Chen, Anzhi, Umansky, Kfir-Baruch, Oonk, Kelsey A., Choi, Wen-Yee, Dickson, Amy L., Ou, Jianhong, Cigliola, Valentina, Yifa, Oren, Cao, Jingli, Tornini, Valerie A., Cox, Ben D., Tzahor, Eldad, Poss, Kenneth D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435404/
https://ncbi.nlm.nih.gov/pubmed/30713073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2019.01.001
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