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Redox-responsive interleukin-2 nanogel specifically and safely promotes the proliferation and memory precursor differentiation of tumor-reactive T-cells
Interleukin-2 (IL-2) is a potent T-cell mitogen that can adjuvant anti-cancer adoptive T-cell transfer (ACT) immunotherapy by promoting T-cell engraftment. However, the clinical applications of IL-2 in combination with ACT is greatly hindered by the severe adverse effects such as vascular leak syndr...
Gardado en:
| Publicado en: | Biomater Sci |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6435399/ https://ncbi.nlm.nih.gov/pubmed/30698174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8bm01556b |
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