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MCAM knockdown impairs PPARγ expression and 3T3-L1 fibroblasts differentiation to adipocytes

We investigated for the first time the expression of MCAM (Melanoma cell adhesion molecule) and its involvement in the differentiation of 3T3-L1 fibroblasts to adipocytes. We found that MCAM mRNA increased subsequent to the activation of the master regulator of adipogenesis, PPARγ, and this increase...

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Publicat a:Mol Cell Biochem
Autors principals: Gabrielli, Matías, Romero, Damián G., Martini, Claudia N., Iustman, Laura Judith Raiger, del C. Vila, María
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435271/
https://ncbi.nlm.nih.gov/pubmed/29468504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-018-3334-8
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