A non-randomized trial to assess the safety, tolerability, and pharmacokinetics of posaconazole oral suspension in immunocompromised children with neutropenia

BACKGROUND: Posaconazole (POS) is a potent triazole antifungal agent approved in adults for treatment and prophylaxis of invasive fungal infections (IFIs). The objectives of this study were to evaluate the pharmacokinetics (PK), safety, and tolerability of POS oral suspension in pediatric subjects w...

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Veröffentlicht in:PLoS One
Hauptverfasser: Arrieta, Antonio C., Sung, Lillian, Bradley, John S., Zwaan, C. Michel, Gates, Davis, Waskin, Hetty, Carmelitano, Patricia, Groll, Andreas H., Lehrnbecher, Thomas, Mangin, Eric, Joshi, Amita, Kartsonis, Nicholas A., Walsh, Thomas J., Paschke, Amanda
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435162/
https://ncbi.nlm.nih.gov/pubmed/30913226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0212837
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